Glaucoma Treatments

GLAUCOMA TREATMENTS
Generic	Brand	Strength	Size	Form	Adult Dose
ALPHA₂-AGONISTS
apraclonidine HCl	—	0.5%	5mL, 10mL	soln¹	1–2 drops 3 times daily
brimonidine tartrate	Alphagan P	0.1%, 0.15%	5mL, 10mL, 15mL	soln²	1 drop every 8hrs
ALPHA₂-AGONIST + BETA-BLOCKER
brimonidine tartrate/ timolol maleate	Combigan	0.2%/ 0.5%	5mL, 10mL	soln¹	1 drop every 12hrs
BETA-BLOCKERS
betaxolol HCl	—	0.5%	5mL, 10mL, 15mL	soln¹	1–2 drops twice daily
betaxolol HCl	Betoptic S	0.25%	2.5mL, 5mL, 10mL, 15mL	susp¹	1–2 drops twice daily
carteolol HCl	—	1%	5mL, 10mL, 15mL	soln¹	1 drop twice daily
levobunolol HCl	Betagan	0.5%	5mL, 10mL, 15mL	soln¹	1–2 drops once or twice daily
metipranolol HCl	Optipranolol	0.3%	5mL, 10mL	soln¹	1 drop twice daily
timolol hemihydrate	Betimol	0.25%, 0.5%	5mL, 10mL, 15mL	soln¹	1 drop twice daily
timolol maleate	Istalol	0.5%	5mL	soln¹	1 drop once daily in the morning
	—	0.25%, 0.5%	5mL, 10mL	soln¹	Initially 1 drop of 0.25% twice daily; max 1 drop of 0.5% twice daily
	Timoptic Ocudose	0.25%, 0.5%	60	soln⁴
	Timoptic-XE	0.25%, 0.5%	2.5mL, 5mL	gel-forming soln	1 drop once daily
CARBONIC ANHYDRASE INHIBITORS
acetazo– lamide	Diamox Sequels	500mg	100	sust-rel caps	500mg twice daily
brinzolamide	Azopt	1%	2.5mL, 5mL, 10mL, 15mL	susp¹	1 drop 3 times daily
dorzolamide HCl	Trusopt	2%	10mL	soln¹	1 drop 3 times daily
methazo– lamide	—	25mg, 50mg	contact supplier	tabs	50–100mg twice to three times daily
CARBONIC ANHYDRASE INHIBITOR + ALPHA-AGONIST
brinzo– lamide/ brimonidine tartrate	Simbrinza	1%/0.2%	8mL	susp¹	1 drop three times daily
CARBONIC ANHYDRASE INHIBITOR + BETA-BLOCKER
dorzolamide HCl/ timolol maleate	Cosopt	2%/0.5%	10mL	soln¹	1 drop twice daily
dorzolamide HCl/ timolol maleate	Cosopt PF	2%/0.5%	0.2mL	soln⁴	1 drop twice daily
CHOLINERGIC (MIOTIC) AGONISTS
pilocarpine HCl	Isopto Carpine	1%, 2%, 4%	15mL	soln¹	2 drops up to 3–4 times daily or more if needed. Heavily pigmented irides: need higher concentrations.
CHOLINESTERASE INHIBITORS
ecothiophate iodide	Phospholine Iodide	0.125%	5mL	soln	1 drop twice daily, in the AM and at bedtime. Apply finger pressure to inner canthus for 1–2mins after instillation.
PROSTAGLANDIN ANALOGS
bimatoprost	Lumigan	0.01%, 0.03%	2.5mL, 5mL, 7.5mL	soln¹	1 drop once daily in the PM
latanoprost	Xalatan	0.005%	2.5mL	soln¹	1 drop once daily in the PM
latanoprost	Xelpros	0.005%	2.5mL	emul– sion	1 drop once daily in the PM
latanoprostene bunod	Vyzulta	0.024%	5mL	soln¹	1 drop once daily in the PM
tafluprost	Zioptan	0.0015%	0.3mL	soln⁴	1 drop once daily in the PM
travoprost	Travatan Z	0.004%	2.5mL, 5mL	soln³	1 drop once daily in the PM
RHO KINASE INHIBITORS
netarsudil	Rhopressa	0.02%	2.5mL	soln¹	1 drop once daily in the PM
Rho Kinase Inhibitor + Prostaglandin Analog
netarsudil/ latanoprost	Rocklatan	0.02%/ 0.005%	2.5mL	soln¹	1 drop once daily in the PM
NOTES
Key: soln = solution; sust-rel caps = sustained release capsules; susp = suspension ¹Contains benzalkonium chloride. May be absorbed by soft contact lenses. ²Contains purite. ³Contains sofZia (boric acid, propylene glycol, sorbitol, zinc chloride). ⁴Preservative-free. Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. (Rev. 7/2019)

Want to read more?