Oral Allergy Treatments: Rx

ORAL ALLERGY TREATMENTS: Rx
Generic	Brand	Strength	Form	Dose
ALLERGEN EXTRACT
short ragweed pollen allergen extract (Ambrosia artemisiifolia)	Ragwitek	12 Amb a 1‑U	sub– lingual tabs	Children: <18yrs: not established. Adults: Initiate ≥12wks before onset of ragweed pollen season and continue throughout season. Give 1st dose under physician supervision; observe ≥30mins for severe allergic reaction; if tolerated, subsequent doses may be taken at home. 18–65yrs: 1 tab daily.
timothy grass pollen allergen extract	Grastek	2800 BAUs	sub– lingual tabs	Adults and Children: <5yrs: not established. Initiate at least 12wks before onset of grass pollen season and continue throughout season. Give 1st dose under physician supervision; observe ≥30mins for signs/symptoms of a severe allergic reaction; if tolerated, subsequent doses may be taken at home. ≥5−65yrs: one tab daily.
ANTIHISTAMINE (FIRST GENERATION H₁ ANTAGONIST)
carbinoxamine maleate	—	4mg	scored tabs	Children: <2yrs: Contraindicated. 2−5yrs: 0.2−0.4mg/kg/day in 3−4 divided doses. 6−11yrs: 2−4mg 3−4 times daily. Adults: 4−8mg orally 3−4 times daily.
	—	4mg/ 5mL	soln
	Karbinal ER	4mg/ 5mL	ext-rel oral susp	Children: <2yrs: Contraindicated. 2−3yrs: 3.75−5mL (3−4mg) every 12hrs; 4−5yrs: 3.75−10mL (3−8mg) every 12hrs; 6−11yrs: 7.5−15mL (6−12mg) every 12hrs. Adults: 7.5−20mL (6−16mg) every 12hrs.
cyprohepta– dine HCl	—	4mg	scored tabs	Children: <2yrs: not recommended. 2−6yrs: 2mg 2−3 times per day; max 12mg daily. 7−14yrs: 4mg 2−3 times per day; max 16mg daily. Adults: ≥14yrs: Initially 4mg 3 times daily; usual range 12−16mg/day; max 0.5mg/kg per day.
hydroxyzine HCl	—	10mg, 25mg, 50mg	tabs	Children: <6yrs: 50mg daily. ≥6yrs: 50−100mg daily. Both in divided doses. Adults: 25mg 3−4 times daily.
hydroxyzine HCl	—	10mg/ 5mL	syrup†
hydroxyzine pamoate	Vistaril	25mg, 50mg	caps	Children: <6yrs: 50mg daily. ≥6yrs: 50−100mg daily. Both in divided doses. Adults: 25mg 3−4 times daily.
ANTIHISTAMINE (SECOND GENERATION H₁ ANTAGONIST)
desloratadine	—	2.5mg, 5mg	ODT*	Adults and Children: Dissolve on tongue; swallow with or without water. <6yrs: use other forms. 6−11yrs: 2.5mg once daily. ≥12yrs: 5mg once daily. Renal or hepatic impairment: Initially 5mg every other day.
	Clarinex	5mg	tabs	Children: Use other forms. Adults: 5mg once daily. Renal or hepatic impairment: Initially 5mg every other day.
	Clarinex	0.5mg/ mL	syrup	Adults and Children: <6mos: not recommended. 6−11mos: 1mg (2mL). 1−5yrs: 1.25mg (2.5mL). 6−11yrs: 2.5mg (5mL). ≥12yrs: 5mg (10mL). All: Once daily.
LEUKOTRIENE RECEPTOR ANTAGONIST
montelukast (as sodium)	Singulair	10mg	tabs	Adults and Children: Take granules by mouth within 15min of opening packet; may dissolve in 5mL of cold or room temperature baby formula or breast milk, or mix in spoonful of soft applesauce, carrots, rice, or ice cream. <6mos w/perennial allergic rhinitis or <2yrs w/seasonal allergic rhinitis: not established. 6−23mos: one 4mg granule packet. 2−5yrs: One 4mg chew tab or granule packet. 6−14yrs: One 5mg chew tab. ≥15yrs: One 10mg tab. For all: Take once daily.
		4mg, 5mg	chew tabs*
		4mg/ packet	oral gran– ules
ANTIHISTAMINE + SYMPATHOMIMETIC
acrivastine/ pseudoephe– drine HCl	Semprex-D	8mg/ 60mg	caps	Children: Not established. Adults: 1 cap every 4−6hrs, max 4 caps/day.
desloratadine/ pseudoephe– drine sulfate	Clarinex-D 12 Hour	2.5mg/ 120mg	ext-rel tabs	Children: Not recommended. Adults: Swallow whole. 1 tab every 12hrs.
desloratadine/ pseudoephe– drine sulfate	Clarinex-D 24 Hour	5mg/ 240mg	ext-rel tabs	Children: Not recommended. Adults: Swallow whole. 1 tab once daily.
NOTES
Key: ODT = orally disintegrating tablets; soln = solution; * = contains phenylalanine; † = contains alcohol. Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. (Rev. 10/2019)

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