Two novel, non-coaxial ring-focus contact lens designs demonstrate the ability to slow axial length (AL) elongation, with 1 of the designs significantly reducing spherical equivalent autorefraction (SECAR) compared with single vision contact lenses, according to a study published in Ophthalmology Science.
Researchers included 185 children with myopia in a multi-center, randomized, controlled, double-masked study and randomized them to treatment with 1 of the 2 non-coaxial ring-focus designs (enhanced efficiency, n=44; enhanced vision, n=49), a dual focus design (n=45) or single vision contact lenses (n=47). Post-cycloplegia AL and SECAR measurements were performed at baseline and at 1-, 4-, 13-, and 26-week follow-up visits.
At the final visit, participants fit with the enhanced efficiency, enhanced vision, and dual focus designs experienced significantly less axial elongation compared with individuals fit with SV contact lenses (0.079 mm; 0.119mm; 0.135 mm; 0.189mm, respectively). However, only individuals fit with the enhanced efficiency design experienced significantly less SECAR progression compared with participants fit with the SV lenses (-0.12 vs -0.35 diopters [D]). Study participants in the enhanced efficiency group also experienced significantly less AL growth compared with individuals in the dual focus group (least square mean difference, -0.049 mm; 95% CI, -0.093 to -0.004).
Changes in AL and SECAR for the enhanced vision and dual focus designs were not statistically different. Patients fit with all 3 myopia control lenses had a mean visual acuity close to 0.00 logarithm of the minimum angle of resolution (logMAR) with an estimated 95% CIs less than 0.10 logMAR.
Patients fit with enhanced efficiency and dual focus designs were more likely to report halos, but no serious ocular adverse effects were reported.
“The non-coaxial ring-focus technology of the prototype lenses used in this study offers potential performance advantages over traditional coaxial focus lenses and may mitigate the trade-off between efficacy and visual quality with such designs,” according to the researchers.
The short duration is an acknowledged study limitation.
Disclosure: This research was supported by Johnson & Johnson Vision. Please see the original reference for a full list of disclosures.
Cheng X, Xu J, Brennan NA. Randomized trial of soft contact lenses with novel ring focus for controlling myopia progression. Ophthalmol Sci. Published online October 18, 2022. doi:10.1016/j.xops.2022.100232