Long-term soft multifocal contact lens wear does not affect accommodative amplitude, lag or facility when used as a pediatric myopia control method, according to research published in Optometry and Vision Science.
Researchers conducted an analysis of children (age range, 7-11 years) with myopia from the Bifocal Lenses In Nearsighted Kids (BLINK) 1 and 2 studies (ClinicalTrials.gov Identifiers: NCT02255474 and NCT04080128, respectively) and randomly assigned participants to treatment with single vision, +1.50 D add, or +2.50 D add center-distance soft multifocal contact lenses. Study individuals underwent accommodative response measurements to a 3 D stimulus at baseline and annually for 3 years and accommodative amplitude, accommodative lead, accommodative lag, and binocular facility measurements with ±2.00 D flippers after an average 4.7 years. The investigators compared the 3 accommodative measures utilizing multivariate analysis of variance, adjusting for clinic site, sex, and age group (7-9 vs 10-11 years).
Participants who wore the +2.50 D add multifocal contact lenses demonstrated lower accommodative response compared with the single vision contact lens wearers for 3 years, but the +1.50 D add multifocal contact lens wearers only showed lower accommodative response compared with the single vision contact lens wearers for 2 years.
Following adjustment for clinic site, sex, and age group, no statistically significant or clinically meaningful differences were noted between the 3 treatment groups for accommodative amplitude (P =.49), accommodative lag (P =.41), or accommodative facility (P =.87) after an average of 4.7 years of contact lens use.
“This was the first randomized clinical trial to investigate the effects of long-term multifocal contact lens wear on accommodation in children,” according to the researchers. “Eye care practitioners prescribing multifocal contact lenses for myopia control should not be concerned about causing long-term effects on accommodation.”
This study was limited by a failure to conduct accommodative measures throughout the entire study duration while wearing the myopia control lenses.
Disclosure: One study author declared affiliations with biotech, pharmaceutical, and/or device companies. Please see the original reference for a full list of authors’ disclosures.
Chandler MA, Robich ML, Jordan LA, et al. Accommodation in children after 4.7 years of multifocal contact lens wear in the BLINK study randomized clinical trial. Optom Vis Sci. Published online June 26, 2023. doi:10.1097/OPX.0000000000002040